The B2SLab research group, which is part of the Biomedical Engineering Research Centre (CREB UPC), is taking part in a study that, for the first time, will investigate genetic factors and the impact of extreme sport on respiratory immunity in elite sportspeople. The study, which is led by Emma Roca, an elite sportsperson and biochemist, will be carried out on a hundred runners in the Zurich Marathon of Barcelona on 13 March. The physiological, biochemical and cardiac state of the subjects will be assessed before, during and after the race. CREB UPC will carry out a bioinformatic analysis of gene expression and the analysis of signs of variability in the heart rate of the runners. Other participants in the study include the Unit of Genomics of Complex Diseases and the Immunological Laboratory of the Biomedical Research Institute Sant Pau (IIB Sant Pau); the Sant Pau Pneumonology Services; the University of Girona (UdG); and the Zurich Barcelona Marathon.